[Download] "Effect of Culture Substrata and Fibroblast Inhibitors: Trigeminal Ganglion Axon Outgrowth Revisited (Report)" by Pakistan Journal of Zoology * eBook PDF Kindle ePub Free

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eBook details

• Title: Effect of Culture Substrata and Fibroblast Inhibitors: Trigeminal Ganglion Axon Outgrowth Revisited (Report)
• Author : Pakistan Journal of Zoology
• Release Date : January 31, 2010
• Genre: Life Sciences,Books,Science & Nature,
• Pages : * pages
• Size : 204 KB

Description

Byline: Irfan Zia Qureshi and Martin E. Atkinson - Email: irfan_qureshi_pk2007@yahoo.com Abstract.- Axon outgrowth in vitro can be influenced profoundly by the culture system used and may even be misleading due to certain prerequisites. Intact non-dissociated trigeminal ganglia extend neurites only when cocultured with target tissues and not in isolation. We set out to determine if intact early age murine trigeminal ganglia extend neurites in isolation, is it the culture system involved and whether fibroblast inhibitors could actually prevent the normal outgrowth pattern. Mouse intact trigeminal ganglia before target innervation were given the choice to grow in isolation or with target tissues on three dimensional collagen gels, collagen coated platform and poly-d-lysine substrata. Cultures in this way were set up in the presence and absence of fibroblast inhibitors.

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